Job Title: Senior Scientist/Principal Scientist/Associate Director - DMPK Location: Exton, Pennsylvania Department: Drug Metabolism and Pharmacokinetics (DMPK) Reports to: Assistant Vice President

Job Summary:

We are seeking an experienced and highly motivated Senior Scientist, Principal Scientist, or Associate Director to join our DMPK team. This position offers the opportunity to work in a dynamic environment that supports drug discovery and development programs.

Key Responsibilities: Conduct in vitro and in vivo ADME studies using radiolabeled and non-radiolabeled compounds. Perform sample analysis using a range of analytical instruments, including sample oxidizers, liquid scintillation counting (LSC), and LC/MS. Manage labs to ensure proper instrument maintenance and documentation of equipment/instruments usage, calibration, and services. Prepare study protocols, oversee study conduct, collect and summarize data, and write/review reports to meet study timelines. Ensure all lab operations and record-keeping are of high quality and compliant with Frontage SOPs, DMPK guidelines, study protocol and applicable regulations. Manage multiple tasks/projects simultaneously to meet internal/external deadlines, fostering collaboration within the DMPK team. Provide training and mentorship to junior scientists in key areas of drug development. Demonstrate expertise in leading cross-functional, matrix-based project teams, taking accountability and guiding them to successful outcomes. Provide scientific leadership and direction to clients and development teams for ongoing and prospective programs Qualifications: PhD in Biochemistry, Pharmacology, Chemistry, or a related field with 5-10+ years of relevant experience, or a Master's degree with 10-15+ years of experience in DMPK, ADME, or a related field. Significant experience in leading ADME studies, particularly with radiolabeled compounds. Proven leadership experience in managing teams and delivering on tight deadlines while maintaining high standards of data quality. Excellent communication and leadership skills, with the ability to collaborate effectively across functions and levels. Familiarity with GLP compliance and EPA rules/regulations is a plus.

Frontage Laboratories Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, among other things, or status as a qualified individual with disability