Overview Location: South San Francisco, CA - Hybrid, with the ability to be in office 2-3 days per week Position Summary: As Program Team Lead (PTL) early development focused initially on our lead clinical stage program, you will be driving execution of the program vision and strategy and play a central role in steering the program towards its goals. You will oversee planning, resources, budgets and activities ensuring program deliverables stay on track as we work toward bringing this important therapy to patients. In this role, your leadership will be critical in facilitating key decisions, collaborating with a cross-functional program team and company leadership, and integrating their input into the program’s development. Strong clinical, scientific, pharmaceutical development and project management experience is required, along with excellent communication skills and organizational leadership experience. Clinical development experience across geographies is strongly. Responsibilities Influence and lead teams through stakeholder discussions to help frame and obtain approvals for the asset strategy, including funding and scope Establish and maintain integrated global development plans outlining key cross-functional activities required to achieve program milestones Work closely with cross-functional teams, including research, clinical, regulatory, manufacturing, quality, project management, etc, to implement development plans and ensure seamless integration and coordination of program activities Help monitor and optimize the allocation of resources across the program to maximize program efficiency and productivity Identify risks and implement mitigation strategies Bring strong business acumen with a perspective that includes an understanding of the external development and commercial landscape Organize and lead certain cross functional project team meetings, helping set agendas and drive key decisions in collaboration with project management Play a critical role in building inclusive high performing teams by creating an environment of cooperation and respect, influence and facilitate teams to obtain approvals for asset strategy, investment and scope Facilitate the publication of data in appropriate peer-reviewed platforms with abstract, posters, and both presentation and manuscripts Help organize and run scientific advisory boards; interact with external experts from time-to-time as needed Required Qualifications Advanced degree; a doctorate or other advanced degree, in a scientific field is, higher degrees or certifications (MS, MBA, PMP, etc) will also be considered 10+ years of experience in drug development, including leading Program Teams through early development (first in human through Phase 2) Experience in clinical stage drug development, particularly in dermatology or other immunology and/or autoimmune disease areas Demonstrated ability to lead cross-functional multidisciplinary teams effectively Strong understanding of regulatory processes, technical operations, market access, and commercialization A strategic, innovative thinker Excellent communication skills and organizational leadership experience Opportunities Support the development of life changing therapeutics Collaborate with and helped build a world class team Compensation: $190,000 - $260,000, plus Discretionary Bonus TRexBio is a clinical stage biotechnology company leveraging cutting edge computational biology tools, a focus on human tissue, and expertise in immunobiology to develop revolutionary therapeutics for inflammatory diseases. Our powerful ‘deep biology’ discovery engine maps human tissue Treg behavior to disease processes, allowing us to identify and characterize novel targets for therapeutic intervention. Leveraging this platform, we are building a broad portfolio of novel therapies that modulate the immune system to restore human tissue immune homeostasis. Our Culture At TRexBio, you will have the opportunity to work with world class researchers who strive to make the world a better place. In addition to our team-centric culture, we believe that your individual creativity will help us to be our best. Our staff happy hours, organized by our Culture Club, bring us all together in creative and social activities. Our colleagues admire and respect one another. We celebrate our wins, update company news and acknowledge each other’s achievement weekly and monthly at all company meetings that celebrate our work and our people. TRexBio is proud to be an AA/EEO employer and all qualified candidates will receive consideration without regard to characteristics protected by applicable local, state, or federal law, such as race, color, religion, sex, national origin, age, disability, marital status, veteran or military status, genetic information, or other protected characteristics.

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