General Summary:

Vertex seeks a dynamic and experienced Medical Affairs Physician/ Senior Medical Director for our Disease Area of Hematology within the Medical Affairs Strategy group. This individual will be responsible for the execution of medical strategies for the first FDA approved CRISPR-cas9 medicine (Exa-Cel) for the treatment of Sickle Cell Disease and Transfusion dependent B-Thalassemia, including providing medical leadership for the assigned therapeutic area and will be responsible for developing the medical strategy and medical plan as well as executing against the medical plan for assigned therapeutic areas and/or products. This role reports to the Global Medical Lead for Hematology and will collaborate closely with cross-functional groups to ensure that scientific and medical strategies are aligned with broader corporate and key stakeholder needs as well as ensuring the voice of the patient and medical community is integrated into product strategies.

Key Duties and Responsibilities: Develops medical affairs plans, including Launch and Life Cycle Management plans Critically interprets scientific data, determines the potential impact of new research on clinical practice, and uses scientific and clinical data to formulate frameworks and disease management approaches Provides input from medical community into clinical development and commercial strategies Effectively communicates scientific data through presentations and publications Ensures country/regional insights and needs are considered in global medical strategies and activities Provides scientific input and expertise as a medical reviewer and supports the development of global medical, commercial, regulatory, and reimbursement documents Performs/oversees medical/scientific training for Medical, Commercial, and other internal stakeholders Reviews investigator-sponsored study (ISS) proposals and other research grants Knowledge and Skills: Deep understanding of global medical, regulatory and commercial (including payer) environments Excellent understanding of government and industry guidelines, regulations, laws, etc., for appropriate scientific/medical exchange and communication with key external stakeholders (e.g., healthcare providers, payers, advocacy bodies) Deep understanding of market access in key countries Excellent written and oral communication skills to influence others internally/externally Ability to develop relationships in a highly matrixed environment, as well as external relationships with global, regional and local thought leaders and industry experts Ability to engage in positive dialogue and resolve conflicts in a constructive manner Education and Experience: The successful candidate will have a medical degree from a well-regarded institution and at least 8 years of experience in industry leading clinical and/or medical programs. The ideal candidate will have sub-specialty training in Hematology or Hematology/Onclology . Experience in Marrow /Hematopoetic Transplant.is a plus. 8 plus years of experience in the biotechnology or pharmaceutical industry, with 5 in Medical Affairs; including experience working with thought leaders and direct involvement in promotional and medical materials review. Typically requires experience in a Medical Affairs function and in the analysis of research (pre-clinical or clinical) data and publications; working knowledge of biostatistics as well as scientific and clinical research methods, and clinical study design

Pay Range: $288,000 - $431,900

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation: Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid : work remotely up to two days per week; or select 2. On-Site : work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com