Overview At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We are focused on leading a revolution in oncology to redefine cancer care and address the unmet needs of patients around the world. We are following the science to understand cancer and all its complexities so that we can discover, develop and deliver life-changing treatments and increase the potential for cure. The Oncology business is the fastest growing team within AstraZeneca and across the industry. Through our relentless quest for innovation, we have created one of the most diverse portfolios and pipelines in the industry. We deliver on the promise of our pipeline through launch excellence, commercial effectiveness and maximizing the lifecycle. Role Director of Pathology Diagnostics, Global Oncology Diagnostics is accountable for the development and execution of global scientific strategy related to pathologic diagnosis, including Digital and Computational Pathology and Molecular Pathology, for AstraZeneca oncology diagnostic solutions worldwide. This role supports the advancement and integration of digital and computational pathology methods to transform cancer diagnostics and leverage data-driven approaches for improved accuracy and reproducibility. This role supports the mission of AstraZeneca Oncology in four domains: Maximizing Global Biomarker Adoption and facilitating the development of local testing solutions through innovative digital and computational pathology platforms

Generating Clinical and Analytic Evidence in collaboration with Oncology Medical Affairs and external Diagnostic Partners

Developing Medical Education for the lab community to support the adoption of local testing with a strong focus on digital and computational pathology best practices

Leading efforts for the generation of real-world data for Pathology diagnostic solutions harnessing digital and computational pathology analytics and technologies

What You’ll Do The Director of Clinical Diagnostics will work closely with cross-functional partners, regions, and countries for coordination of all Oncology diagnostic activities. The role involves collaborating on the development of the global medical plan for patient identification solutions for AstraZeneca Oncology products and partnering with all relevant cross-functional collaborators to implement the Oncology Diagnostics medical strategy with an emphasis on digital and computational pathology platforms. The role also includes assisting in the development of KEE advocacy and KEE engagement plans in laboratory segments, leading Scientific Advisory boards and other diagnostics activities at scientific events including major Congresses and Forums. The Director will also be responsible for championing AstraZeneca’s leadership in digital and computational pathology at major scientific events and forums. Minimum Qualifications MD or DO degree from an accredited medical school, or holds a PhD

+ 5 years of experience in medical affairs, global diagnostics, biopharmaceutical industry, and/or academia including experience or substantial exposure to digital and/or computational pathology

Preferred Qualifications MD with accredited pathology residency and fellowship in a clinical or molecular subspecialty

Strong life sciences foundation (e.g., Molecular Biology, Pathology), with experience in clinical companion diagnostic development using digital and computational pathology methodologies

Membership in relevant diagnostics professional societies

Over 5 years of Medical Affairs experience in biotech, pharmaceutical, or CRO settings, including collaborations with integrated delivery networks, accountable care organizations, and payers

Skilled in stakeholder engagement, including KEE, advocacy groups, and payers

Familiarity with global regulatory organizations, guidelines, Good Clinical Practice (GCP), and pharmaceutical product development, encompassing clinical operations, commercial, regulatory, and medical affairs aspects of companion diagnostics and digital/computational pathology

Demonstrated scientific and medical judgment, problem-solving abilities, and a practical understanding of scientific methods and clinical applications in digital and computational pathology

Proven success working collaboratively within matrixed, cross-functional teams

Location This position can be based at our Gaithersburg, MD campus (headquarters for the US Oncology and the global Oncology Business Unit), at our Cambridge, UK headquarters or our Mississauga, Canada or Barcelona, ES hub. In-person working is preferred, with a typical expectation of a minimum three days per week in the office, balanced with individual flexibility. Compensation and Benefits AstraZeneca offers an environment where you can thrive by working with new drugs, digital approaches, and ever-changing environments. Our base pay ranges from $247,786 - 371,679 USD, with overtime for eligible non-exempt employees and variable pay opportunities. Benefits include a 401(k) retirement plan, paid vacation and holidays, paid leaves, and medical/dental/vision coverage. Details provided in offer documents. An at-will employment relationship and potential changes to compensation or programs may occur. Dates Date Posted 18-Sept-2025 Closing Date 09-Oct-2025 EEO Statement Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. We welcome and consider applications from all qualified candidates, regardless of protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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