Director, Clinical Operations

Maximise your chances of a successful application to this job by ensuring your CV and skills are a good match. San Diego, CA - Onsite $160,000-$190,000 An emerging biotech company in San Diego is seeking a Director of Clinical Operations to lead early-stage clinical programs in the cardiology space. The company is advancing a novel therapeutic platform focused on gene regulation, with applications in complex diseases such as fibrosis and oncology. This role will be responsible for overseeing clinical trial execution from start-up through completion, including vendor and CRO management, cross-functional coordination, and operational strategy. The ideal candidate will bring strong leadership in trial design, site engagement, and regulatory compliance, along with a hands-on approach to building clinical infrastructure in a fast-paced, science-driven environment. Key Responsibilities: Lead execution of Phase 1 and 2 trials, including investigator-initiated studies Collaborate on protocol development and trial design Manage CROs, vendors, and external partners Coordinate across clinical science, regulatory, biostats, and other functions Oversee drug supply logistics and biospecimen management Develop and implement enrollment strategies and patient-facing materials Ensure GCP/ICH compliance and clinical quality systems Support safety monitoring and pharmacovigilance activities Manage study budgets, site payments, and financial tracking Serve as primary liaison for clinical sites and oversee site performance Contribute to data integrity, interim analyses, and reporting Qualifications: Bachelor's or Master's in life sciences or related field 8+ years in clinical operations with experience leading trials end-to-end Strong understanding of global clinical development and regulatory standards Proven experience managing CROs and clinical vendors Skilled in budgeting, forecasting, and site payment systems Excellent communication and problem-solving skills Experience in RNA-based therapies, cardiology, or rare disease is a plus Willingness to travel as needed for site oversight If you are interested in hearing more, please dont hesitate to apply.