Associate Scientific Director

Working with Us Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services, and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Business Unit Summary Our Drug Product Development team is committed to CMC design, development, and commercialization of innovative drug products to improve patient lives. We leverage the best people, collaboration, and cutting-edge innovation to achieve this commitment. BMS's internal engine of innovation includes unrivaled industry leading expertise in CMC development of small molecules, protein biotherapeutics, protein degraders, and other therapeutic modalities. We collaborate closely with our colleagues in R&D and Commercial to design our drug products. Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope.

Position Summary In the Product Development organization at BMS, predictive sciences are central to enabling our "model first" strategy to accelerate development and enable bringing more medicines to patients faster. We are seeking an experienced and highly motivated Associate Scientific Director to join the Integrated Technology and Engineering group in the Drug Product Development (DPD) organization. In this role, the individual will lead the development and application of predictive modeling approachesfrom first-principles mechanistic models to hybrid, molecular, machine learning techniques to digital twinsacross both small molecule and biologics modalities (including oral solid dosage forms, sterile products, antibody-drug conjugates, and other modalities) to support drug product development. The individual will serve as a key scientific leader to integrate modeling into process and formulation development workflows, enhancing process understanding, risk assessment, and reducing development and tech transfer timelines. This includes driving the use of molecular modeling approaches to support formulation design and development, enabling data-driven decisions early in the development lifecycle. This role will champion a "modeling-first" culture in the organization, collaborating with cross-functional teams both within the Drug Product Organization and partner functions to enable data-driven decisions. An ideal candidate brings a good balance of experience in formulation/process development for drug product development and expertise in building/implementing model-based tools/platforms to aid decisions in formulation/process development. This position will maintain accountability towards the modeling strategy and deliverables, and depending on candidate experience and organizational needs, may also include people management responsibilities.

The successful candidate thrives in a diverse team environment, driving inclusion by exemplifying the BMS Core Values, understanding the impact of privilege, creating space for underrepresented groups, and mitigating implicit bias. The individual works well with people from other disciplines and thrives in a multifunctional team environment. If you want an exciting and rewarding career that is meaningful and directly helps deliver lifesaving medicines to patients, consider joining our diverse team!

Key Responsibilities

• Develop and implement a comprehensive modeling strategy aligned with organizational goals for drug product development through internal and external partnerships.
• Provide technical mentorship and training, clearly communicating complex modeling approaches and outcomes to technical peers and senior leadership.
• Lead modeling efforts for oral solid dosage processes to predict critical product attributes, manufacturability, and scale-up performance, sterile drug product process modeling and device-related interactions (e.g. fluid dynamics in devices etc.).
• Leverage material attribute and molecular modeling approaches to inform formulation design and development, linking material attributes to product attributes and performance.
• Apply and champion advanced mechanistic, molecular, hybrid, and machine learning modeling approaches to enhance predictive capability, formulation design, process design, optimization, risk assessment, and technology transfer.
• Engage stakeholders and functional leaders across formulation, process engineering, quality, device, packaging, and manufacturing teams to embed and drive a "model-first" culture into decision-making workflows.
• Oversee model-informed experimental designs and targeted data collection for robust model validation.
• Identify and implement innovative modeling and simulation technologies to maintain industry leadership.
• Manage and/or mentor a team of modeling scientists, depending on experience and organizational needs.

Qualifications & Experience

• Ph.D. in Chemical Engineering, Pharmaceutical Sciences, Mechanical Engineering, Material Science engineering or related discipline with 10-12 years of relevant experience; or M.S. with 13-15 years of relevant industry experience.
• Solid experience in mainstream drug product development, including material science, formulation, process scale-up, technology transfer, and manufacturing across oral and sterile modalities.
• Demonstrated expertise in first principles, hybrid, ML models, and computational methods (e.g., DEM, CFD, population balance, flow sheet modeling) with application to digital twin development and application
• Strong knowledge of.
• Proficiency in computational tools (e.g., gPROMS, Aspen, Ansys) and programming languages (e.g., Python, MATLAB, R).
• Proven ability in stakeholder management and driving organizational change toward model-driven development.
• Familiarity with digital infrastructure, data integration, and workflow automation.
• Excellent collaboration and interpersonal skills within matrix organizations.
• Exceptional communication and presentation skills.

Preferred:

• Track record of innovation demonstrated through publications, presentations, or patents.
• Experience leading modeling initiatives and influencing adoption of modeling strategies.
• Prior experience of managing or mentoring scientific teams.

Note: Pharmacokinetic (PK), physiologically based pharmacokinetic (PBPK), and biopharmaceutics modeling are explicitly out of scope for this role.

The starting compensation for this job is a range from $166,200 - $201,400, plus incentive cash and stock opportunities (based on eligibility). The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year's holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as "Transforming patients' lives through science ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion, and integrity bring out the highest potential of each of our colleagues.

On-site Protocol BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based, and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive company culture. For field-based and remote-by-design