Overview Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value. The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules. We are seeking a pharmacometrician to join our Clinical and Quantitative Pharmacology organization in Translational Medicine. An Associate Director or Director is responsible for executing on the pharmacometrics strategy and model-based analyses for clinical drug development and is expected to play a key role in supporting programs. This role will be responsible for developing and implementing model-informed drug development (MIDD) strategies to optimize decision-making across all phases of drug development. Candidates will be evaluated on a case-by-case basis whether their experiences aligns with the Associate Director or Director requirements. Essential Functions of the Job (Key responsibilities) Responsible for independently conducting and reporting model-based analyses including population pharmacokinetics (PK) and pharmacokinetics/pharmacodynamics (PK/PD), exposure-response modeling, model-based meta-analyses (MBMA), disease progression modeling, and clinical trial simulation. Identifies opportunities where modeling and simulation can advance the understanding of pharmacokinetics, pharmacodynamics, efficacy, and safety across multiple projects Accountable for developing MIDD strategies across multiple programs and disease areas to optimize prospective studies, inform the overall clinical development and regulatory strategies in collaboration with partners (clinical pharmacology, biostatistics, regulatory, and clinical development teams) Effectively communicates results, conclusions, and assumptions of pharmacometrics analyses to a variety of audiences to influence the decision-making process (written and oral presentation) Mentors and guides peers in pharmacometrics methodologies, tools, and their application in clinical drug development Stays current with scientific advancements and regulatory trends in clinical pharmacology and pharmacometrics, and applies the knowledge to advance drug development for the organization Publishes in peer-reviewed journals Qualifications (Minimal acceptable level of education, work experience, and competency) Ph.D. in Pharmacometrics, Clinical Pharmacology, Applied Mathematics, Statistics, Engineering, or a related field. Demonstrated 3-5 years (for Associate Director) or 5-8 years (for Director) of related industry experience. Hands-on experience in a statistical programming language and pharmacometrics analysis software including R and NONMEM or equivalents Excellent communication skills and ability to collaborate with cross-functional teams. Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required. Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer. We Respect Your Privacy Learn more at: http://www.incyte.com/privacy-policy The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate.

During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process here. You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may also have a right to report concerns to the authority responsible for data privacy in the country where the position is based or where you live or work. You can learn more about Incyte's data protection practices here. By accessing this link you can learn about the types of personal data we collect, how we use it, whether collection and processing is optional, sources of the personal data we process, how it is shared, where it is stored or transferred to, how long we keep it, and contact information for Incyte, Incyte's data protection officer, and your supervisory authority (if applicable). Please contact privacy@incyte.com if you have any questions or concerns or would like to exercise your rights.