Overview

Senior Director, Statistical Programming. Base pay range: $265,000.00/yr - $290,000.00/yr. Retrieved from the description. Our people share why they joined Rapport and love it here: it comes down to three things—the science, the mission, and the team. Rapport is focused on developing precision neuromedicines with potential for fewer side effects, enabling patients and families to enjoy healthier lives. The platform centers on Receptor Associate Proteins (RAPs) and targets indications such as focal epilepsy, with additional trials for neuropathic pain and bipolar disorder. Rapport values its Rapptors—the team members who bring heart and hustle to advance science while upholding our core values. Your Impact

The Senior Director of Statistical Programming is responsible for providing comprehensive leadership and strategic guidance for all statistical programming activities within Rapport’s clinical development programs. The role reports directly to the Vice President of Biometrics and shapes the strategy and long-term vision for the Biometric group’s capabilities, technology infrastructure, and operational processes. Your Day-to-Day

Lead and manage the Statistical Programming function across all stages of clinical development (Phase I-IV), from protocol development to submission and post-marketing activities. Drive strategic planning and resource allocation for programming activities across studies and programs. Oversee the design, development, validation, and documentation of SAS programs for data analysis, TFL (tables, listings, figures) generation, and CDISC deliverables (SDTM, ADaM). Ensure compliance with industry standards (CDISC, ICH, FDA/EMA guidance) and Rapport SOPs. Provide programming oversight for regulatory submissions (e.g., NDA/BLA/MAA), including eCTD packages, data packages, and reviewer guides. Lead the development and implementation of programming standards, automation tools, and quality control processes. Serve as a subject matter expert for programming strategy, data standards, and regulatory expectations. Collaborate with Biostatistics leadership to ensure integration of statistical and programming workflows. Build and mentor a high-performing programming team; provide coaching, career development, and performance management. Manage outsourcing strategy and oversee deliverables from CROs and external vendors. Contribute to cross-functional initiatives to improve data quality, efficiency, and innovation in clinical development. Must-Haves

Master’s or Bachelor’s degree in Computer Science, Statistics, Mathematics, Life Sciences, or a related field. 12+ years of experience in statistical programming within the biotech/pharmaceutical industry. Proven ability to build, lead, and develop high-performing programming teams, with a demonstrated track record of mentoring talent, fostering a collaborative culture, and aligning team objectives with broader organizational goals. Expert-level proficiency in SAS (Base, Macro, STAT, GRAPH) and experience with CDISC standards (SDTM, ADaM). Proven track record of supporting successful regulatory submissions (e.g., NDA, BLA, MAA). In-depth knowledge of clinical trial processes, GCP, regulatory requirements (FDA, EMA), and ICH guidelines. Strong project management skills and ability to manage multiple priorities in a fast-paced environment. Experience managing and developing high-performing teams, both internal and external (CRO/vendor). Excellent interpersonal, communication, and leadership skills. Familiarity with R, Python, or other programming languages is a plus. Experience in Neurology or CSN highly desirable. What Makes Rapport Special

Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start. We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities. Your perspective matters. Share your ideas—we work as a team. We have FUN. We hire smart, dedicated, down-to-earth people that you’ll enjoy spending time with. Leadership that CARES – about you, your growth + development. We’re bicoastal. Whether you’re in the lab full-time in San Diego or hybrid in Boston, we make the most of our time together. Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and more! You get to be YOU! Show up as you are and make every day count. Your Compensation

We tell you about our hiring range now. The anticipated range for this role is $265,000 to $290,000. Your actual offer will reflect factors including relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, Rapport offers a strong benefits package and full salary ranges for every level across the company. Hybrid Work Environment

We prioritize in-person connection with Rapptors. Our team members come onsite to the Boston office on Tuesday and Wednesday. In January 2026, this will shift to three days a week to create more opportunities for innovation, collaboration, and connection. Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. Note to Employment Agencies

Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited. CCPA disclosure notice can be found here. Seniority level

Director Employment type

Full-time Job function

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