POSITION SUMMARY:

The Director, Project Management (PM) and Process Excellence is a strategic and hands-on leader responsible for overseeing the execution of client programs, building strong client partnerships, and driving continuous improvement across operations within a radiopharmaceutical CDMO environment. The Director, PM and Process Excellence will lead a cross-functional team to ensure on-time, in-scope, and on-budget delivery of complex client projects, while also fostering a culture of operational excellence to improve efficiency, quality, and scalability in manufacturing and support functions. Additionally, the Director will help mature the PMO by establishing standardized practices for project governance, portfolio management, and resource planning, while ensuring the PMO delivers measurable value to business leaders and external clients.

PRINCIPAL RESPONSIBILITIES:

Project & Program Management

• Oversee planning and execution of client development and manufacturing projects, including tech transfers, scale-up, validation, and commercial production.

• Lead a team of project managers and coordinators to ensure projects meet timelines, budgets, and regulatory requirements.

• Demonstrate full project life cycle ownership from initiation of a technical transfer from a client to completion of routine contract manufacturing of a radiopharmaceutical drug product.

• Serve as escalation point for project risks, delays, or resource constraints.

• Develop and maintain comprehensive project dashboards and reporting structures for internal and client visibility.

Change Management

• Act as a senior leader overseeing key organizational change initiatives, ensuring high levels of stakeholder engagement, transparency, and trust.

• Coordinate with cross-functional teams during the planning and initiation of change projects to ensure alignment with strategic objectives.

• Facilitate change readiness assessments, stakeholder communications, and progress reviews to support smooth transitions and adoption.

• Translate organizational goals and change drivers into actionable change management strategies and implementation plans.

Client Management

• Act as senior point of contact for key CDMO clients, ensuring high levels of satisfaction, transparency, and trust.

• Coordinate with business development and commercial teams during client onboarding and project initiation.

• Facilitate client meetings, business reviews, and ongoing communications to ensure alignment and satisfaction.

• Translate client needs into actionable internal strategies and project plans.

Operational Excellence

• Champion Lean, Six Sigma, and continuous improvement initiatives across manufacturing, quality, and support areas.

• Identify process inefficiencies and lead cross-functional improvement projects with measurable outcomes.

• Implement performance metrics (KPIs) to monitor and drive operational performance.

• Collaborate with functional leaders to develop standardized workflows, visual management, and digital tools for project tracking and operations management.

Cross-Functional Leadership

• Work closely with Quality, Manufacturing, Engineering, Supply Chain, and Regulatory Affairs to align on execution and strategic priorities.

• Facilitate governance and decision-making structures for integrated project execution and continuous improvement.

• Perform other duties as assigned.

People Leadership

• Build and lead a high-performing process excellence and project management team.

• Mentor senior leaders and managers on continuous improvement, change management, and structured problem-solving.

• Promote collaboration across scientific, operational, and commercial functions.

QUALIFICATIONS & REQUIREMENTS:

• Bachelor’s degree in engineering, Business Administration, or a related field. A Master’s degree (e.g., MBA or MS in Engineering) is preferred.

• 8+ years of external or client-based project management experience required.

• Certification as a Project Management Professional (PMP), Master Project Manager (MPM) or Professional in Project Management (PPM) or equivalent required.

• 8+ years Pharmaceutical, biotechnology with specific contract manufacturing or radiopharmaceuticals, or advanced manufacturing demonstrated project management work experience preferred.

• A deep understanding of the unique challenges and regulatory requirements of the radiopharmaceutical industry, including handling of radioactive materials and cGMP (current Good Manufacturing Practice).

• Demonstrated success in building and leading enterprise-level BPM and PMO functions.

• Exceptional leadership, influencing, and change management skills.

• Ability to thrive in a fast-paced, client-focused, and highly regulated environment.

• Demonstrated problem solving skills, communication skills, time management, collaboration, team building and organizational skills.

• Proficient with project management methodologies and tools (Microsoft Project, monday.com, smartsheet etc).

• Familiarity with regulatory requirements (e.g. OSHA, EPA, NRC) and quality standards (e.g., GMP, FDA, EMA).

• Ability to run effective project meetings, workshops and conferences.

• Highly organized with strong attention to detail and commitment to high quality work.

• Travel up to 30% expected as position / company grows

THE FINE PRINT:

The salary range for this position is $150,000 - $200,000 per year. Please note that compensation may vary outside of this range depending on several factors, including but not limited to a candidate’s qualifications, skills, competencies, experience, and location.

Benefit packages for this role include medical, dental, and vision insurance, as well as a Health Savings Account or Flexible Spending Account options (depending on the plan chosen), and 401k retirement account access with employer matching. Team members in this role are also entitled to paid sick leave and/or other paid time off in compliance with applicable law. Relocation is available to qualified team members.

This job description is a summary of the typical functions of the position, not necessarily an exhaustive or comprehensive list of all possible position responsibilities, tasks, and duties. The company reserves the right to assign or reassign duties and responsibilities to this job at any time. This job does not constitute a written or implied contract of employment; employment remains “at-will”.

Nucleus RadioPharma is an equal opportunity employer and believes everyone deserves respect, dignity, and equality. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.