About Madrigal: Madrigal is a biopharmaceutical company pursuing novel therapeutics for non-alcoholic steatohepatitis (NASH), also known as metabolic dysfunction associated steatohepatitis (MASH). Our first therapy, Rezdiffra (resmetirom), was granted accelerated approval by the U.S. Food and Drug Administration (FDA) for the treatment of adults with NASH with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis) and is being studied in a Phase 3 trial for the treatment of NASH with compensated cirrhosis. Position Responsibilities: Accountable for the successful execution of clinical studies. Successfully manages studies within agreed timelines and budget and in alignment with all the applicable SOPs and regulatory requirements. Ensure compliance with FDA and global health authority regulations and guidelines and internal operating procedures and processes as well as ICH/GCP guidelines. Initiate collaborative relationships with external institutions/representatives when required. Initiate procurement of external resources, consultants, or equipment when protocol requires. Develop strategies for efficient study conduct, data collection, subject management and safety monitoring. Coordinate efforts inter-departmentally to accomplish these strategies. Independently design, develop and review study related documents including but not limited to: clinical protocols, case report forms, site study manuals and project tools, monitoring plans, tracking tools, informed consent forms, and anything else deemed relevant. Assist with the development and review of regulatory submissions. Responsible for tracking study milestones to ensure accurate tracking and reporting of study metrics and timelines. Lead study management team meetings and teleconferences with study vendors and properly manage all study deliverables as appropriate. Support clinical operations in preparation and/or attendance at departmental meetings, training and developmental activities as required and directed. Assist with creation of departmental SOPs and process documents, as needed. Qualifications and Skills Required: Bachelors degree required, health sciences preferred 10+ years of experience with a Minimum of at least 5 years of experience in the biopharmaceutical, CRO industry or other relevant work history, managing all aspects of a clinical study from start to finish. Preferred TA experience in hepatology, GI, diabetes or metabolic syndrome. Experience with TMF, Site communication, and Budgets Organizational project manager experience, grounded in studies. This role will require 3 days onsite in Conshohocken, PA Compensation: Base salary is determined by several factors that include, but are not limited to, a successful candidate's qualifications, skills, education, experience, business needs, and market demands. The role may also be eligible for bonus, equity, and comprehensive benefits, which include flexible paid time off (PTO), medical, dental, vision, and life and disability insurance. Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.

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